Detection of mutations and damaged DNA bases is important for the early diagnosis of genetic disease. Here we describe an electrocatalytic method for the detection of single-base mismatches as ...

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

PARG inhibition results in increases in sensitivity to DNA damage and disrupted DNA replication ... 2,4 Here, PARylation is an indicator of approach efficacy, and products such as the LysA™ Universal ...