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尽管Pol III进入延伸状态后,与通用转录因子的直接相互作用被打破,但这些因子仍稳定结合在启动子上游区域(图3)。 长期以来,科学界推测Pol III起始因子在一次转录完成后不会立即脱离DNA,而是保留在启动子附近,便于迅速启动新一轮转录。
In view of the recent observation that pol ν may have a role in cellular tolerance to DNA cross-linking agents, our findings provide biochemical evidence for the potential functioning of this ...
This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...
The increasing demand for donor hearts presents both a critical challenge and a significant opportunity for innovation in ...
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