Sequences that form DNA secondary structures, such as G‐quadruplexes (G4s) and intercalated‐Motifs (iMs), are abundant in the human genome and play various physiological roles. However, they can also ...

In view of the recent observation that pol ν may have a role in cellular tolerance to DNA cross-linking agents, our findings provide biochemical evidence for the potential functioning of this ...

北京时间2025年6月4日晚间，复旦大学徐彦辉研究团队在《自然》（Nature）杂志在线发表题为“Structural insights into human Pol III transcription initiation in ...

经济观察网讯 据分子植物科学卓越创新中心消息，近日，中国科学院分子植物科学卓越创新中心巫永睿团队与张余团队，联合上海师范大学王文琴团队，发现了植物质体DNA（ptDNA）复制体中RNA引物切除的核心核酸酶组分plastid-localized and Mn2+-dependent 5′-3′exonuclease ...

In E. coli, activity of both DinB (DNA pol IV) and UmuD' 2 C (DNA pol V) is strongly influenced by interactions with the β processivity clamp of DNA polymerase III (pol III) (10, 17, 18) and the umuD ...

The Battle of Drøbak Sound was a remarkable confrontation of the Second World War, where an outdated fort manned by recruits managed to sink one of the Kriegsmarine's newest warships, the ...

Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC ...

The Cr (III)-DNA binding can be dramatically reduced by the ability of the reaction medium (e.g., phosphate buffer) to form complexes with Cr (III) during and after the disproportionation reaction. A ...

尽管 Pol III 进入延伸状态后，与通用转录因子的直接相互作用被打破，但这些因子仍稳定结合在启动子上游区域（图 3）。 长期以来，科学界推测 Pol III 起始因子在一次转录完成后不会立即脱离 DNA，而是保留在启动子附近，便于迅速启动新一轮转录。

Festival of Archaeology at Salisbury Museum to featuring expert who identified King Richard III's remains.