Bart Westendorp and his team study DNA replication. They use the latest technologies, such as single cell sequencing, live cell imaging, and flow cytometry. They study multiple cancer types, including ...

Protein complex in bacterial cell membrane acts like a rotary motor to recruit DNA-degrading enzymes to defend against phage ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

由于基因组异质性，单细胞复制时间（scRT）在癌症中的研究具有挑战性。在这里，作者开发了MnM，这是一种机器学习工具，可以提供异质性分辨率的scRT文件，并将其应用于包括肿瘤、细胞系和患者来源的异种移植物在内的大型单细胞数据集。

Research reveals that DNA mutations may influence epigenetic clocks, raising new questions about the aging process.

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

Covalent bonding is a widely understood phenomenon that joins the atoms of a molecule by a shared electron pair. But in ...

Jumbo phages utilize a complex protein import system, with Imp1 as a key gatekeeper, to transport proteins into their ...

Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD ...

DNA (deoxyribonucleic acid) is the nucleic acid polymer that forms the genetic code for a cell or virus. Most DNA molecules consist of two polymers (double-stranded) of four nucleotides that each ...

Fanconi anemia (FA) is a rare genetic disorder characterized by defective DNA repair, leading to hematopoietic stem cell (HSC) dysfunction and bone marrow failure. Replication stress, which ...