Using a new technology and computational method, researchers from Fred Hutch Cancer Center and The University of Texas MD Anderson Cancer Center have uncovered a biomarker capable of accurately ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

Covalent bonding is a widely understood phenomenon that joins the atoms of a molecule by a shared electron pair. But in ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

由于基因组异质性，单细胞复制时间（scRT）在癌症中的研究具有挑战性。在这里，作者开发了MnM，这是一种机器学习工具，可以提供异质性分辨率的scRT文件，并将其应用于包括肿瘤、细胞系和患者来源的异种移植物在内的大型单细胞数据集。

These non-living materials will have capabilities including self-healing, adaptation, growth, and programmability.

Fanconi anemia (FA) is a rare genetic disorder characterized by defective DNA repair, leading to hematopoietic stem cell (HSC) dysfunction and bone marrow failure. Replication stress, which ...

近期，哥本哈根大学诺和诺德基金会蛋白质研究中心的研究人员在npj Precision Oncology期刊上发表了一篇题为 “Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma” ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

We live in a golden age for space exploration. Scientists are gathering massive amounts of new information and scientific ...

[Editors' note: this paper was reviewed by Review Commons.] Cancer cells display high levels of oncogene-induced replication stress (RS) and rely on DNA damage checkpoint for viability. This feature ...