Mammalian cells are capable of loading MCM2-7 to support DNA replication in the absence of ORC to permit extensive DNA replication in vivo.

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for all life to grow and reproduce. For the first time, scientists have directly ...

Supreme Court Justices Appear Narrowly Divided Over Death Row Prisoner Plea for DNA Testing The justices heard arguments in the case of a man on death row in Texas who claims DNA testing could ...

There are no effective antivirals against BK polyomavirus in transplanted kidneys. A better understanding of its replication will offer new ways to protect those kidneys. BK polyomavirus, or BKPyV, is ...

As cells divide, they must copy all of their chromosomes once and only once, or chaos would ensue. How do they do it?

Problems during DNA replication can cause the genome to become disorganized, which is often a key step on the route to cancer. Some genetic diseases, too, result from problems with DNA replication.

In our bodies, there are trillions of cells. DNA is the foundation of organisms, but what does it stand for? Get to know more about this nucleic acid.

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study. The work solves a mystery that has long puzzled biologists.

Replication stress induces phosphorylation events within RIF1 intrinsically disordered region that are essential for RIF1's role in DNA replication fork protection.

Slowing DNA replication in totipotent cells boosts reprogramming efficiency, promising advances in regenerative medicine. Adult cells in our body can only give rise to the same cell type. For example, ...