Sequences that form DNA secondary structures, such as G‐quadruplexes (G4s) and intercalated‐Motifs (iMs), are abundant in the human genome and play various physiological roles. However, they can also ...

Enzymes are involved in virtually every biological process that occurs throughout the body. This includes but is not limited ...

A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

Mammalian cells are capable of loading MCM2-7 to support DNA replication in the absence of ORC to permit extensive DNA replication in vivo.

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for all life to grow and reproduce. For the first time, scientists have directly ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged DNA.

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified.

Recent findings reveal that early mouse embryos replicate their DNA in a unique, uniform manner, which changes after the embryo grows beyond four cells. This early-stage replication is slower and more ...

When it comes to DNA replication, humans and baker's yeast are more alike than different Date: August 1, 2024 Source: Van Andel Research Institute Summary: Humans and baker's yeast have more in ...