Each replication fork synthesises a leading strand in the same direction as the fork progression and a lagging strand synthesised as 100-200bp discontinuous Okazaki fragments in the opposite direction ...

Xiang et al. investigated the role of ubiquitin E3 ligase ITCH in SARS-CoV-2 replication. First, they described the role of ITCH on the structural proteins. Here, the ubiquitination of E and M (but ...

I was one of the first to spit into a test tube, giving up my DNA forever to learn more about my health and heredity. You know, the ones that promise to connect you with distant relatives you didn ...

The origin of the Huns in fourth-century Europe has long been debated, but centuries-old DNA has revealed their diverse backgrounds. Skip to main content Open menu Close menu ...

Univ Brest, Ifremer, Biologie et Ecologie des Ecosystèmes Marins Profonds (BEEP), Plouzané, France In my opinion, these discoveries challenge the “classical” models of DNA replication. Archaea are not ...

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk. Thousands of ...

Ancient DNA is telling us more and more about humans and environments long past. Could it also help rescue the future? Eske Willerslev was on a tour of Montreal’s Redpath Museum, a Victorian-era ...

British historian Russell Edwards claims to have identified Jack the Ripper as Aaron Kosminski using DNA evidence from a crime scene. Kosminski, a mentally ill Polish immigrant, allegedly committed ...

Over a century after he murdered and mutilated London women in 1888, the long-mythologized killer’s identity has allegedly been confirmed by DNA found on a shawl, historian Russell Edwards said.

The SUMO ligase activity of ... a converging fork will complete replication. However, if a single fork stops within the rDNA or telomere, it will result in a region of DNA that cannot be replicated.