When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations ...

The DNA damage response (DRR) is an integrated series of pathways that dictate the cellular response to DNA damage and replication stress. The DDR is actively being pursued therapeutically to treat ...