They observe how the mobile DNA LINE-1 copies its sequence in human cells, revealing the precise mechanism of the ORF2p gene.

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Learn how to simplify the entire DNA template generation workflow, streamlining mRNA therapeutic research. Successful in vitro transcription (IVT) and translation for therapeutic applications require ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

KAUST scientists have captured the moment DNA begins to unwind, revealing how helicases use ATP to initiate replication. This breakthrough uncovers energy-efficient mechanisms that could inspire ...

DNA replication is one of the most well-orchestrated cellular processes that needs to proceed in a faithful and timely manner. However, this process is continuously challenged, leading to stalled ...

Abstract: We consider a nonlinear inverse problem where the unknown is assumed to be piecewise affine, which is motivated by an application in DNA replication analysis. Since traditional algorithmic ...

Univ Brest, Ifremer, Biologie et Ecologie des Ecosystèmes Marins Profonds (BEEP), Plouzané, France In my opinion, these discoveries challenge the “classical” models of DNA replication. Archaea are not ...

If these DNA breaks aren't repaired, they can prompt cells to self-destruct, or failing that, become cancerous. As LIG4 syndrome impairs this response, people with the condition are particularly ...