Credit: Kateryna Kon/Science Photo Library/ What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and answer questions ...

Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958?

And one of the things it can get stuck on is the DNA template itself, ... gained attention as potential therapeutic targets ...

The replication fork is more than just a means for DNA duplication. It is connected to a checkpoint system that keeps the genome intact and prevents cancer. Aa Aa Aa Eukaryotic genomes are ...

For DNA to be copied, the DNA double helix must open up, and the resulting single strands—each of which serves as a template for building a new, second strand—are vulnerable to breakage. Or ...

Cellular RNA can template DNA repair in yeast Date: September 3, 2014 Source: Georgia Institute of Technology Summary: RNA produced within cells of a common budding yeast can serve as a template ...

Fig. 4. The replisome is capable of translesion DNA synthesis. The left part of the figure shows the template DNA used and the position of the template damage (UN, undamaged; THF, tetrahydrofuran ...

Sandra Small, senior manager of science education and workforce development, is Co-I on a $2.45 million R01 grant from the National Institute of General Medical Sciences that will fund exploration of ...

Scientists have shown that RNA produced within cells of a common budding yeast can serve as a template for repairing the most devastating DNA damage -- a break in both strands of a DNA helix.

Cryo-electron microscopy reveals hidden mechanics of DNA replication, sheds new light on cancer target Date: March 10 ... And one of the things it can get stuck on is the DNA template itself, ...

And one of the things it can get stuck on is the DNA template itself, which can adopt alternative structures in certain contexts. For example, regions of the genome that are rich in guanine bases ...