Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

Strand invasion occurs in a highly sequence-specific manner through direct Watson−Crick base pairing. Unlike the previously developed double-duplex invasion strategy, which requires simultaneous ...

Using an inexpensive electrode coated with DNA, MIT researchers have designed disposable diagnostics that could be adapted to ...

Universal Primer technology is used to crack wildlife crime cases, from ivory trafficking in Odisha to illegal bushmeat ...

Double-strand DNA breaks articles from across Nature Portfolio A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing ...

This project investigates how different DNA repeat configurations (direct, inter-inverted, intra-inverted) affect gene-strand bias through inversion events. The model demonstrates: Null Model Behavior ...

Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.

During repair, the DNA reads the uracil as thymine. Although there's no double-stranded break, base editors do create a nick in one strand.

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

Innovation in biotechnology has reached new heights with the advancement of microbial genome editing services. These services enable researchers and industries to modify the genetic makeup of ...