The 1.9-Å-resolution crystal structure of the nucleosome core particle containing 147 DNA base pairs reveals the conformation of nucleosomal DNA with unprecedented accuracy. The DNA structure is ...

It is this alternating sugar-phosphate arrangement that forms the "backbone" of a DNA molecule. Figure 3: All polynucleotides contain an alternating sugar-phosphate backbone.

2024年4月4日，南方科技大学鄢仁鸿课题组在Structure上在线发表题为 Structural basis for the inhibition mechanism of the DNA polymerase holoenzyme from mpox virus（抑制猴 ...

NAR：揭示dna环境影响吸烟相关癌症风险的分子机制. 来自耶路撒冷希伯来大学等机构的科学家们通过研究绘制出了这些损伤图谱，从而揭示了机体dna ...

2022 年 7 月 15 日，浙江大学生命科学学院赵烨教授、华跃进教授联合浙江大学医学院郭江涛教授团队在 CellPress 旗下的 Structure 杂志发表了题为“ Mechanisms of helicase activated DNA end resection in bacteria ”的研究成果。 该论文使用冷冻电镜首次解析了细菌中的损伤 DNA 末端降解复合体 HerA-NurA ...

The discovery of DNA structure by James Watson and Francis Crick in the year 1953 is one of the most revolutionary scientific discoveries to date. However, the research leading to the discovery of ...

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to ...

Watson and Crick describe structure of DNA 1953 Photo: Model of DNA molecule. In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were ...

The two strands of DNA form a 3-D structure called a double helix. When illustrated, DNA looks like a spiral ladder in which the base pairs are the rungs, and the sugar-phosphate backbones are the ...

In the second step, the AMP is transferred to the 5’-end of the 5’-phosphate-terminated DNA strand to form DNA-adenylate — an inverted pyrophosphate bridge structure, AppN. In this reaction, the ...

Water molecules surround the genetic material DNA in a very specific way. Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) have discovered that, on the one hand, the texture of this ...

Water molecules surround the genetic material DNA in a very specific way. Scientists have discovered that, on the one hand, the texture of this hydration shell depends on the water content and, on ...