Polyethyleneimines (PEIs) are extensively researched as non-viral vectors for gene and medication delivery because of their ...

Dr. Ahmed Lawan, an assistant professor in the College of Science at The University of Alabama in Huntsville (UAH), a part of The University of Alabama System, has published a paper in the journal ...

Some eukaryotes consist of a single cell; but most single-celled creatures are made of simpler cells which lack obvious ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

C-G base pairs in the DNA structure require more energy to break these bonds. Therefore, a higher abundance of C-G base pairs in the DNA structure increases the melting temperature. Divalent Cations ...

This valuable work presents an interpretable protein-DNA Energy Associative (IDEA) model for predicting binding sites and affinities of DNA-binding proteins. While the method is convincing, it ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. FANCM is crucial in genome maintenance, ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

DNA hydrogels are biocompatible drug delivery systems for targeted therapeutic interventions. Conventional DNA hydrogels, formed with many DNA nanostructure units, lead to increased preparation costs ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Endonuclease III (EndoIII), a key enzyme in the base excision repair (BER) pathway, ...