DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

Researchers discovered a previously unknown function of RNA, potentially opening the door to new ways to treat cancer and neurodegenerative diseases.

RNA (ribonucleic acid) is a nucleic acid polymer where the carbohydrate is ribose. RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is ...

Linked to neurological disorders, repeat RNAs aggregate inside droplets but can be disassembled with an engineered piece of ...

A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

RNA folding articles from across Nature Portfolio Atom RSS Feed RNA folding is the process by which a linear ribonucleic acid (RNA) molecule acquires secondary structure through intra-molecular ...

When the COVID-19 pandemic swept across the world in 2020, the mRNA vaccines came to the rescue of many people—but in the ...

New research has shown how harmful RNA clusters form in neurological disorders, and how they can be prevented and ...

为攻克这一难题，研究人员将目光投向自然界广泛存在的RNA-DNA杂合体结合机制。 RNaseH1蛋白的RNA-DNA hybrid binding domain (RHBD)因其特异性识别杂交双链的特性成为理想候选。 通过将人类RNaseH1的RHBD1结构域与ABE8e、BE4max等编辑器融合，研究团队构建了新型嵌合编辑器系统。

RNA structure-function relationship Submissions should provide detailed, in-depth knowledge about the different aspects of RNA, in all its variety and versatility, thus gaining insights into molecular ...

Methods Adaptive sampling long-read DNA sequencing targeted to 19 colon cancer genes, paired with direct long-read RNA whole-transcriptome sequencing, was undertaken for four patients referred for ...