微小 RNA（miRNAs）大多通过影响 DNA-PKcs 来影响化疗或放疗中的 DNA 损伤修复（DDR），如 miR-488-3p 可调节恶性黑色素瘤细胞对顺铂的敏感性 34。 DNA-PKcs 在可变剪接中的作用：可变剪接（AS）是产生转录组多样性的重要机制，DNA-PKcs 参与前体 mRNA 的可变剪接。

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

编辑推荐： 为探究 DNA 甲基转移酶 1（DNMT1）相关突变导致迟发性神经退行性疾病的机制，研究人员开展了关于 DNMT1 与 RNA 甲基化及线粒体功能关系的研究。结果发现 DNMT1 可调节 RNA m5C 甲基化影响线粒体功能，为相关疾病致病机制研究提供新视角。

灵敏度差异 DNA在病原体中通常为单拷贝,而RNA以多拷贝形式存在 (如一个肺炎支原体中含约1000-10000个核糖体RNA拷贝)。

Linked to neurological disorders, repeat RNAs aggregate inside droplets but can be disassembled with an engineered piece of ...

RNA，作为生命活动的中心分子之一，其功能远不止于转录 DNA 信息。近年来，RNA 的结构多样性及其在生物学过程中的关键作用越来越受到关注，研究 ...

研究发现RNA通过一个名为TET2的基因，在DNA如何包装和储存在细胞中起着重要作用。 在每个细胞内，在每个细胞核中，你的持续生存取决于一场极其 ...

Discover methods for accurate DNA and RNA quantification and learn how to analyze purity and concentration to enhance reliability in molecular biology.

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...

Base pairs are the fundamental units of nucleic acids, formed by complementary nucleobases bound by hydrogen bonds. They play crucial roles in genetics, DNA structure, and biotechnology applications.