Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, that can lead to poor egg quality, which in turn can cause infertility, ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Lloyd et al employ an evolutionary comparative approach to study how sleep deprivation affects DNA damage repair in Astyanax mexicanus, using the cave vs surface species evolution as a playground. The ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals.

The team from Hebrew University of Jerusalem focused on benzo(a)pyrene, toxic chemical in cigarette smoke, disrupts its ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

If these DNA breaks aren't repaired, they can prompt cells to self-destruct, or failing that, become cancerous.As LIG4 syndrome impairs this response, people with the condition are particularly ...

to locate and monitor the kinetic process of DNA damage induced by ROS in real-time, facilitating the investigation of both global and localized damage. We found that topological differences of DFNs ...

DNA damage can persist unrepaired for years, particularly in blood stem cells, increasing the risk of mutations and cancer. This discovery challenges traditional views on mutation processes and ...