本研究针对滤泡性淋巴瘤(FL)中V-ATPase突变导致溶酶体/液泡脱酸化却意外激活自噬的现象，通过酵母模型发现V-ATPase依赖的自 ...

The transmembrane Na/K-ATPase is located in the plasma membrane of all mammalian cells. It utilizes energy from ATP hydrolysis to execute its pumping function and interacts with other proteins and/or ...

Abstract: Mechanical stress on cells is transmitted through many biological processes, for example, cell shape control, tissue patterning, and axonal homeostasis. Microtubules, a cytoskeletal ...

The manuscript by Verma et al. is a simple and concise assessment of the in-cell motility parameters of cytoplasmic dynein. Although numerous studies have focused on understanding the mechanism by ...

A mechanism of dynein-powered metastatic locomotion has been identified using soft tissue models, revealing a new clinical target for breast cancer treatment. New research led by Penn State (PA, USA) ...

Understanding how a molecular transport system inside neurons works could be used for therapeutic approaches to neurodegenerative disease. A team of neurobiologists at The Molecular Neuroscience Unit ...

Researchers have uncovered the mechanism by which a protein facilitates the spread of breast cancer cells from the primary tumor into healthy tissue. The discovery not only improves our understanding ...

Metastasis is a challenging aspect of breast cancer that makes it difficult to cure. This process involves the spread of cancer cells from the breast to other parts of the body, like the lungs, bones, ...