1 State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, China 2 Yunnan Key Laboratory of ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. In this work, Neiswender and colleagues test the hypothesis ...

When cells divide, the mitotic spindle segregates the genetic material. Correct bipolar spindle assembly depends on mitotic motors with distinct properties. How motors collectively organize ...

1 College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, United States 2 College of Dental Medicine, Western University of Health Sciences, Pomona, CA, ...

Most of us will probably be able to recall at least vaguely that a molecule called ATP is essential for making our bodies move, but this molecule is only a small part of a much larger system. Although ...

Kinesin superfamily members have evolved a variety of N- and C-terminal linkers, which tether the motors to their cargoes. The docking of these linkers against the motor domain exerts force and in ...

Introduction: The post-mitotic cardiomyocyte (CM) must maintain proteostasis while also preserving the ability to remodel, particularly during times of cardiac growth. How the CM couples transcription ...

Instantaneous Flow Tracker accurately analyzes protein flows in mitotic spindles and filamentous actin meshworks in regions with highly dynamic, anti-parallel networks where previous methods failed ...

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