However, atrophy can be prevented, and vocal learning retained in females when given early pharmacological estrogen treatment. To screen for candidate drivers of this sexual dimorphism, we performed ...

Proteovant Therapeutics today announced it will present data on PVTX-321, an estrogen receptor degrader, at the Protein Degradation & Targeting Undruggables Congress USA, March 15-16 in Boston and on ...

CD4 + T cells temporally transition from protective to pathological during ischemic heart failure (HF; 8 weeks postmyocardial infarction). Cellular mechanisms mediating this shift are unknown.

We also observed a prominent estrogen receptor-β (ER-β) expression in the skin samples, especially on keratinocytes. Subsequently, we confirmed the effects of E2 on psoriasis using ER-β antagonist ...

Here we unveil a novel role of Rspo1 in promoting estrogen receptor alpha (Esr1) expression, hence regulating the output of steroid hormone signaling in the mouse mammary gland. This action of Rspo1 ...

The targeted agonist of estrogen receptor beta was predicted from the effective components of Asarum, which is a famous Chinese herbal medicine. In addition, the interactions between the active ...

Several studies have reported that estrogen receptor beta (ERβ) decreases during tumor development in the breast epithelium. However, the role of ERβ in relapse and metastasis of breast cancer is ...

Estrogen Receptor β and Oxytocin Interactions in Regulation HPA Axis and Anxiety-Related Behaviors Activation of ERβ reduces HPA axis activity, as seen by reductions in ACTH levels and CORT levels, in ...

Published: 25 March 2014 Estrogen receptor β and Liver X receptor β: biology and therapeutic potential in CNS diseases M Warner & J-A Gustafsson Molecular Psychiatry 20, 18–22 (2015) Cite this ...

Estrogen receptor (ER)-β has been shown to possess a tumor suppressive effect, and is a potential target for cancer therapy. Using gene-expression meta-analysis of human malignant pleural ...