The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...

The estrogen receptors (ERs) belong to a group of ligand-inducible transcription factors known as the nuclear receptor superfamily (Laudet et al., 1992). Members of the family share several ...

Published: 25 March 2014 Estrogen receptor β and Liver X receptor β: biology and therapeutic potential in CNS diseases M Warner & J-A Gustafsson Molecular Psychiatry 20, 18–22 (2015) Cite this ...

The clinicopathologic importance of a second estrogen receptor (ER), ER-β, in breast cancers has been intensely studied; however, there is still no real consensus regarding the clinical utility of an ...

Association Between Estrogen Receptor-β Expression and Epidermal Growth Factor Receptor Mutation in the Postoperative Prognosis of Adenocarcinoma of the Lung. If you have the appropriate software ...

Systemic lupus erythematosus is a chronic autoimmune disease in which immune cells invade various organs and unleash harmful inflammatory responses. Estrogen may contribute to the condition, which ...

A receptor mutation that essentially blocks estrogen's action has been identified for the first time in a female, researchers report.

First, target cells for estrogen action contain varying concentrations of homodimers of one or both of two species of estrogen receptors — estrogen receptor α and estrogen receptor β — as ...

Scientists know that estrogen can protect the brain, but the details are hazy. Two new papers, each focusing on a different estrogen receptor, now bring the picture into sharper focus. In the May 13 ...

Discover the essentials of Progesterone Receptor Positive (PR+) Breast Cancer, covering its key characteristics, effective treatments, and what patients can expect for prognosis.

Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At Baylor College of Medicine, Louisiana State University ...

Estrogen receptor expression may help explain why more males have autism Date: September 9, 2014 Source: Medical College of Georgia at Georgia Regents University Summary: The same sex hormone that ...