The physiological effects of estrogens are mediated by two intracellular transcription factors, the estrogen receptors (ERs), that regulate transcription of target genes through binding to specific ...

Cadenza Bio, Inc. today announced that a collaborative study, "Chloroindazole based Estrogen Receptor β ligands with ...

Sex differences in brain and behavior are ubiquitous in sexually reproducing species. One cause of sexual dimorphisms is developmental differences in circulating concentrations of gonadal steroids.

The clinicopathologic importance of a second estrogen receptor (ER), ER-β, in breast cancers has been intensely studied; however, there is still no real consensus regarding the clinical utility of an ...

Imlunestrant is a next-generation, brain-penetrant, oral selective estrogen-receptor (ER) degrader that delivers continuous ER inhibition, even in cancers with mutations in the gene encoding ERα (ESR1 ...

The first estrogen receptor was discovered in the late 1950s, a period that Jan-Ǻke Gustafsson refers to as BC (before cloning). Forty years later, he and colleagues were looking for a completely ...

BioWorld - Thursday, June 19, 2025 Breaking News: Trump administration impacts continue to roil the life sciences sector See today's BioWorld Science Home » A carborane agonist of estrogen receptor β ...

Adenocarcinoma of the lung unrelated to a smoking habit occurs more frequently in women than men, thus suggesting an association between female hormones and development of these tumors. The aim of ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

Systemic lupus erythematosus is a chronic autoimmune disease in which immune cells invade various organs and unleash harmful inflammatory responses. Estrogen may contribute to the condition, which ...