This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

The copper hydroxide [Cu(OH)2] nanopesticide is an emerging agricultural chemical that can negatively impact aquatic organisms. This study evaluated the behavioral changes of zebrafish larvae exposed ...

However, atrophy can be prevented, and vocal learning retained in females when given early pharmacological estrogen treatment. To screen for candidate drivers of ... We found GO terms significantly ...

基于机器学习的3D-QSAR模型预测小分子雌激素受体结合活性的研究及其在评估内分泌干扰潜力中的应用 《In Silico Research in Biomedicine》：Machine learning-based 3D-QSAR models for predicting the estrogen receptor-binding activity of small molecules 【字体 ...

Structure-based virtual screening (SBVS), also known as molecular docking, predicts binding geometries based on structural complementarity between small molecules and a target binding site. SBVS ...

Ferutinin is one of the most potent natural phytoestrogens, which has agonistic activity on estrogen receptors, particularly on the ERα receptor. Ferula may act as an agonist by occupying the empty ...