Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The ...

The genome of Caenorhabditis elegans encodes 284 nuclear hormone receptor, which perform diverse functions in development and physiology. One of the best characterized of these is NHR-49, related in ...

Just as a machine needs specific controls to function, proteins like the estrogen receptor control how cells grow and behave. "We found previously unknown 'molecular switches' within the estrogen ...

Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The findings could lead to the development of new drugs with fewer side effects, ...

and the G-protein-coupled estrogen receptor (GPER). These receptors play distinct roles in mediating the effects of estrogens, which are hormones that influence many bodily functions, including ...

SRC1 was the first cloned steroid receptor co-activator that interacts with steroid hormone receptors to promote ... specific and redundant physiological functions in embryonic and adult tissues.

Discover the role of phytoestrogens, including soy, in menopause management and breast cancer prevention. Learn how these ...

This review summarizes the cell and molecular biology of the OXTR and its downstream signaling cascades, particularly focusing on the vasoactive functions of OXTR signaling in humans and animal models ...

[14] Although there is currently substantial literature on the putative neuroprotective effects of estrogen on cognitive functions in ... presence of estrogen receptors in many regions involved ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.