This article was reviewed by Julia Switzer, MD, FACOG. What Is Estrogen? Everything You Need to Know Estrogen is one of the ...
Study in Cancer Research used mice with one copy of p53 silenced and ER gene expression doubled. Minor alterations in p53 and estrogen receptor-alpha gene expression appear to play a role in ...
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually ...
Imlunestrant is a next-generation, brain-penetrant, oral selective estrogen-receptor (ER) degrader that delivers continuous ER inhibition, even in cancers with mutations in the gene encoding ERα (ESR1 ...
THERE are two hormones responsible for ensuring that a woman’s reproductive system does its job well. The first is estrogen, which regulates the menstrual cycle and prepares the uterus for pregnancy; ...
Recent misclassification (false negative) incidents have raised awareness concerning limitations of immunohistochemistry (IHC) in assessment of estrogen receptor (ER) in breast cancer. Here we define ...
Retrospective Study to Determine Factors Influencing Outcome in Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer Receiving Neoadjuvant Chemotherapy Women with ...
FLD is a metabolic dysfunction encompassing several liver pathologies, ranging from intracellular triglycerides accumulation to severe lipotoxicity and fibrosing steatohepatitis, all of which are ...
Hormones serve as the body’s chemical messengers, orchestrating countless processes from metabolism and growth to mood regulation and reproductive function. When these powerful compounds fall out of ...
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