A novel mechanism of action for hemophilia treatment has emerged with the introduction of Marstacimab. This new human monoclonal IgG1 antibody enhances thrombin production by amplifying the extrinsic ...

Brain Research Center, Zhongnan Hosptial of Wuhan University, Wuhan 430071, China Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan 430071 ...

Potential cell–extrinsic targets include systemic and locally produced hormones, growth factors, adipokines and other adipose-derived factors, and inflammatory mediators. Obesity-responsive host ...

IR induces cellular apoptosis by activating both the intrinsic apoptotic pathway (through proapoptotic proteins-mitochondrial outer membrane permeabilization (MOMP)-Cytochrome c/SMAC/DIABLO ...