1 Department of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China 2 Shenzhen Key Laboratory for Reproductive Immunology of ...

Scientists have uncovered how exercise suppresses appetite through a surprising molecular pathway. A compound called Lac-Phe, produced during intense workouts, directly quiets hunger neurons in the ...

ABSTRACT: The HIPPO signaling pathway critically regulates cell proliferation, apoptosis, and tissue homeostasis, playing a pivotal role in Helicobacter pylori (H. pylori)-associated gastric cancer, a ...

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future. Studies show that people receiving ...

In this valuable study, the authors show the physiological response and molecular pathway mediating the effect of quinofumelin, a developed fungicide with an unknown mechanism. The authors present ...

Although chloride (Cl⁻) is essential in small amounts, its excess can lead to severe cellular toxicity, particularly in sensitive species like apple, citrus, and grapevine. In plant roots, Cl⁻ uptake ...

Excessive alcohol consumption causes alcoholic liver disease, and about 20% of these cases progress to alcohol-associated steatohepatitis (ASH), which can lead to liver cirrhosis and liver failure.

A preclinical study in mice and human tissue has uncovered a molecular pathway that may help to explain why wounds inside the mouth can heal quickly and without scars. The researchers, co-led by teams ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Precision oncology led to the establishment ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Large-scale metabolomic analyses of pan-cancer ...