LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

Gearbox's PAX West Borderlands 4 panel delivered plenty of surprises, but none was more intriguing than the reveal of the game's first Story Pack, Mad Ellie and the Vault of the Damned. Billed as a ...

Abstract: The signal transduction network is essential for eukaryotic cellular communication and response to environmental signals, with disruptions leading to various diseases. As our understanding ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lysophosphatidylinositol (LPI) bioactive ...

Mitochondrial dysfunction is closely associated with the pathogenesis of retinitis pigmentosa (RP), often through the generation of reactive oxygen species (ROS), which disrupts visual signal ...

Osteosarcoma (OS) is the most common primary malignant bone tumor that frequently occurs in children and adolescents. Although neoadjuvant chemotherapy has shown efficacy for OS, the long-term ...

Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...

Background Pathogenic mutations in genes encoding components of the Ras/mitogen-activated protein kinase (Ras-MAPK) pathway cause RASopathy. Here, we describe five unrelated patients with SLE carrying ...

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200433, China Laboratory of Molecular Materials and Devices, Fudan ...

The five-year-old Software Acquisition Pathway (SWP) policy authorized by the fiscal year 2020 National Defense Authorization Act is being reemphasized. A new memo from the Secretary of Defense Pete ...