G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to peptides and ...

Naloxone can reverse an overdose in minutes, but exactly how it does this at the molecular level has previously been unclear.

A new study published in iMetaMed reveals that potassium sorbate, a common food preservative, may cause acute kidney injury ...

In their new study, the LJI scientists are the first to show that GPR25 is induced by a signaling molecule called TGF-β.

For more than 70 years, hydralazine has helped doctors lower dangerously high blood pressure during medical emergencies, ...

The gut microbiome serves as both a biomarker and therapeutic target in diseases like obesity, metabolic syndrome, and ...

Now Vijayanand and his colleagues have discovered the cellular driver that leads to T RM cell development. Their findings, ...

Researchers have found a small but powerful switch inside breast cancer cells that helps them survive stressful conditions.

When doctors detect elevated levels of SerpinB3 in a blood test, it can signal that something is seriously wrong, from hard-to-treat cancers to severe inflammatory conditions. Subscribe to our ...

While the COVID pandemic has thankfully been over for some time now, there is still a considerable number of people in the world (about 400 million) suffering from long COVID. Long COVID is a chronic ...