The aim of this study was to assess the effect of screening and of the formation of the Registry on survival, incidence of CRC and age at onset of CRC, in FAP patients. Methods Patients on the ...

Fibrates, such as gemfibrozil, fenofibrate, and bezafibrate, are helpful in correcting the dyslipidemia seen in patients who have moderate to severe hypertriglyceridemia, often with depressed ...

Galactofuranose (Galf) is present in glycans critical for the virulence and viability of several pathogenic microbes, including Mycobacterium tuberculosis, yet the monosaccharide is absent from ...

Introduction Bicuspid aortic valve (BAV) affects 1% of the general population. NOTCH1 was the first gene associated with BAV. The proportion of familial and sporadic BAV disease attributed to NOTCH1 ...

Scientific and technological advances are lending pressure to expand the scope of newborn screening. Whereas this has great potential for improving child health, it also challenges our current ...

Genetic screening of all probands and families was performed by combining the conventional Sanger method, multiplex ligation-dependent probe amplification and next-generation sequencing using MiSeq ...

Objective— This study compares a novel approach using systematic family screening for patients in Iceland who have familial hypercholesterolemia (FH) with conventional proband screening and assesses .

The genetics and epigenetics of interacting cells over developmental time give rise to organisms and their characteristics. Understanding how genotypes give rise to phenotypes is the core objective of ...

US biotech firm Nucleus Genomics this week launched a first-of-its-kind service letting IVF parents select embryos based on their potential disease risk.

Genetic choices, ethical questions. The software analyzes DNA data from up to 20 embryos, screening for over 900 hereditary conditions and offering insights into traits ranging from disease risk ...