Colon cancer is one type of colorectal cancer (cancer that starts in the colon or the rectum). Here are five symptoms of colon cancer that should never be ignored.

Tumor-liltrating lymphocytes (TILs) are predictive for response to neoadjuvant treatment in tumors. Still, the abundance of tumor-liltrating cell types has not yet been produced in large quantities, ...

This Research Topic highlights a transition to a new age in the study of T-cell cross-reactivity, in which AI-powered structure-guided computational prediction of TCR specificity for polyclonal T-cell ...

They introduce an effective integrated method, 3D Cell Shape Quantification (3DCSQ), for transforming digitized 3D cell shapes into analytical feature vectors, named eigengrid, eigenharmonic&nbsp ...

The objective of this work was to establish prognostic models in stage III colon cancer (CC) on the basis of transcriptomic signatures of the tumor microenvironment (TME) and cell cycle from the ...

Paneth cells provide stem cell niche factors in homeostatic conditions, but the underlying mechanisms of cancer stem cell niche development are unclear. Here, we report that Dickkopf-2 (DKK2) is ...

The abundance and biological contribution of natural killer (NK) cells in cancer are controversial. Here, we aim to uncover clinical relevance and cellular roles of NK cells in colon cancer liver ...

A 3D single-cell imaging pipeline that quantifies cancer cell interaction dynamics with other TME cell types using primary patient-derived samples can elucidate how cell–cell interactions impact tumor ...

Dyadic International and Cygnus Technologies formed a strategic partnership for the quantification of host cell proteins (HCPs) from the filamentous fungus Thermothelomyces heterothallica C-1 cells.