Necrotizing autoimmune myopathy (NAM) (also known as immune-mediated necrotizing myopathy (IMNM)) is becoming increasingly recognized as the most common subset among all the inflammatory ...

Researchers at Johns Hopkins University School of Medicine have identified a subgroup of patients with necrotizing myopathy who have a novel autoantibody specificity that makes them potential ...

Swallowing food was strangely difficult, and he was getting weaker by the day. By Lisa Sanders, M.D. “You have to take your husband to the hospital right now,” the doctor urged over the phone ...

Source Reference: Barbacki A, et al "Immune-mediated necrotizing myopathy and dietary sources of statins" Ann Intern Med 2018; doi:10.7326/L17-0620.

Ra Pharma is developing zilucoplan and zilucoplan extended release (XR) for generalized myasthenia gravis (gMG), immune-mediated necrotizing myopathy (IMNM), and other tissue-based, complement ...

Immune-mediated necrotizing myopathy typically presents with progressive symmetrical proximal muscle weakness and myalgias, although some cases can present with respiratory and esophageal muscle ...

SHANGHAI, NANJING, China and SAN JOSE, Calif., Jan. 31, 2024 /PRNewswire/ -- On Jan. 30, 2024, PNAS published the research paper titled "Single-cell analysis of refractory anti-SRP necrotizing ...

Effectiveness of proprotein convertase subtilisin/kexin type 9 inhibitors in managing hypercholesterolemia post-statin-associated immune-mediated necrotizing myopathy: report of five cases and ...

Precise identification and tracking of HMGCR-reactive CD4+ T cells in the target tissue of patients with anti-HMGCR immune-mediated necrotising myopathy, Annals of the Rheumatic Diseases, 84, 2 ...

Compared with patients who die without COVID-19 infection, patients who die with severe COVID-19 may present with signs of mild to severe myositis.