Comparing block characteristics of mixtures of short/intermediate- and long-acting local anesthetics for peripheral nerve block: a systematic review and meta-analysis ...

Since both intravenous and inhalational anesthetics currently in use produce anesthetic and sedative effects by binding to GABA receptors and/or N-methyl-D-aspartate receptors (NMDA, a subtype of ...

Explores how inhalational anesthetics trigger general anesthesia through interaction with calcium channel RyR1.

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...

A new study uncovers the long-elusive mechanism of inhalational anesthetics by identifying the RyR1 calcium channel as a key molecular target.

Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet themselves.

Since their effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their anesthetic ...

A research team at The University of Tokyo has discovered that inhalational anesthetics activate a protein called type 1 ryanodine receptor (RyR1), which contributes to the induction of general ...