The dimensions refer to m (the number of metabolites), n (the number of reactions ... model.rxnKEGGID n x 1 Column Cell Array of Strings Formula for each reaction in the KEGG format.

Enrichment analyses, including GO, KEGG ... factor-target genes, miRNA-target genes, and drug-target genes were constructed and visualized using Cytoscape to identify key hub gene nodes. Finally, key ...

A total of 3579 lncRNAs, 49 miRNAs, 669 mRNAs, and 890 differentially methylated regions (DMR)-associated genes were differentially expressed between PCOS cases and controls. Pathway analysis ...

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory for Digestive Health, National Clinical Research Center for Digestive Disease, Beijing ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

One of the most significant updates to the genome maps includes the addition of more than 1,100 new protein-coding genes that were previously unidentified. These newly mapped genes offer insights ...

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This large-scale genetic analysis uncovered several genes and biological pathways that were not previously ... in genes associated with nitrogen metabolism, suggesting that this is a key metabolic ...

Increased understanding of signal transduction mechanisms and gene regulation involved in immune responses has created opportunities for the discovery of novel therapeutic compounds useful in treating ...

More information: Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression, Nature Metabolism (2025). DOI ...