Here, we identified a circuit, locus coeruleus descending noradrenergic neurons projecting to the spinal dorsal horn (LC →SDH -NA neurons), that is activated by acute exposure to restraint stress and ...

Smooth muscle cells (SMCs) regulate blood flow distribution via vasoconstriction mediated by α-ARs (α-adrenergic receptors). Plasma membrane cholesterol accumulation affects α 1-AR signaling and ...

WASHINGTON — President Donald Trump made a rare appearance Tuesday with Elon Musk, his most powerful adviser, in the Oval Office before signing an executive order to continue downsizing the ...

This review offers an in-depth and comprehensive examination of the multifaceted mechanisms underlying the interactions between mitochondria and innate immune responses. We will delve into the roles ...

Canadian tech giant Shopify Inc. has listed a U.S. headquarters alongside its home base in Ottawa for the first time in an annual regulatory filing with the U.S. Securities and Exchange Commission. A ...

Mayor Olivia Chow said she wants city staff to thoroughly review the contracts with private companies hired to do snow removal for Toronto amid criticism of the removal process after a series of ...

The irony of Kojima – renowned for crafting convoluted narratives in games – getting lost in Marvel’s storytelling web hasn’t escaped notice. However, his critique emphasizes Marvel’s ...

That’s why having access to accurate and well-researched insights is crucial. In this in-depth CanCentra review, we bring you trustworthy information sourced from reputable crypto forums and ...

Tocilizumab (TCZ), a monoclonal antibody targeting the IL-6 receptor, has emerged as an effective treatment for RA. This narrative review provides an update on TCZ’s efficacy and safety based on data ...

A 2SLGBTQ+ advocate who was discriminated against by 911 dispatchers says she has applied for a judicial review of a ruling by the Alberta Human Rights Tribunal. Marni Panas, a transgender woman ...