Abstract: Candida albicans is an opportunistic pathogen which can cause conditions ranging from simple infections to death in immunosuppressed patients. The microorganism has virulence factors which ...

Rapamycin activates TRPM8 in HEK293 cells and sensory neurons. (A) Time course of the intracellular calcium concentration in HEK293 cells expressing TRPM8, showing robust responses to rapamycin (10 µM ...

将高风险基因提交至CTD数据库，查找对其具有调控作用的单体化合物，并通过参考文献得到它们之间的调控关系[26-27]。将高风险基因提交至COREMINE数据库中寻找其潜在干预中药，以P＜0.05作为筛选标准。 平台声明：该文观点仅代表作者本人，搜狐号系信息发布 ...

This study presents a valuable examination of the prevalence of interactions between amino acids from different periods of Earth's history and coenzymes. While the premise of this work is well founded ...

ABSTRACT: Zika virus (ZIKV), a mosquito-borne flavivirus, has been associated with benign infections for decades. However, it has become a public health concern due to its association with severe ...

This project aims at building an in silico pipeline to identify novel Dengue Virus inhibitors. We will incorporate Machine Learning (ML) and Molecular Modeling techniques into the pipeline. The ...

The COVID-19 pandemic resulting from the spread of SARS-CoV-2 spurred devastating health and economic crises around the world. Neutralizing antibodies and licensed vaccines were developed to combat ...

The rapid spread of SARS-CoV-2 has caused the COVID-19 pandemic, resulting in the collapse of medical care systems and economic depression worldwide. To combat COVID-19, neutralizing antibodies have ...

ABSTRACT: The swine flu, H1N1 virus was outbroken in Mexico and the United States in April 2009 and then rapidly spread worldwide. The World Health Organization declared that the outbreak of influenza ...