Macbecin II was identified as a compound that upregulates MHC-I expression, enhancing immune-mediated cancer cell killing. In ...

Thus, it is likely that one or more of these PPP-associated pathways are implicated in maintaining the metabolic balance after a perturbation. A temporal compartmentalization of the response ...

Previous research revealed that nuclear factor of activated T cells 1 (NFAT1) is a novel regulator of the mouse double minute 2 homolog (MDM2) oncogene, which acts by directly binding to the MDM2 P2 ...

However, high costs associated with assay kits and regulatory challenges may pose constraints to market growth. Metabolic disorders, including amino acid metabolism disorders, phenylketonuria (PKU), ...

Here, we showed a metabolic reprogramming mechanism that enables CRC cells to develop resistance ... Following a 48 h treatment period, a volume of 13 μL of MTS solution (Sigma; #75-79-6) solution (2 ...

Furthermore, the application of bioinformatics methods, such as network pharmacology and molecular docking, could be valuable in identifying specific lung cancer targets of MA and elucidating the ...

Dried blood spot sampling offers a scalable strategy to close diagnostic gaps and improve global surveillance for cardiovascular‐kidney‐metabolic syndrome. However, assay performance and the extent of ...

Researchers conducted a retrospective study to examine the agreement between nurse-assigned and expert-assigned Manchester Triage System (MTS) codes and association with clinical outcomes. They ...