Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

However, the pathogenesis of ALI/ARDS remains a complex issue. In recent years, the role of macrophage pyroptosis in lung injury has garnered extensive attention worldwide. This paper reviews the ...

This study investigates the impact of aging on macrophage metabolic dysfunction and its consequences for atherosclerosis regression, addressing a critical issue given the aging global population. Aged ...

More information: Isabel Gordaliza-Alaguero et al, Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy, Autophagy (2024). DOI: 10.1080 ...

Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy. Autophagy , 2024; 1 DOI: 10.1080/15548627.2024.2440843 Cite This Page : ...

Korea Bioactive Natural Material Bank, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea ...

Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry and College of Chemistry, Nankai University, ...

The study offers mechanistic insights into how different impairments in lipid metabolism lead to diverse antimicrobial responses, including glycolysis, oxidative stress, and autophagy. This deepens ...

and cardiac macrophage phenotypes. Consequently, pharmacological targeting of autophagy in this condition could represent a possible therapeutic strategy to limit MI-induced cardiac damage, adverse ...

Most of these cellular changes were not captured by mRNA profiling, and included activation of ubiquitin-mediated autophagy, an evolutionarily ancient cellular antimicrobial system. This analysis also ...