By augmenting macrophage TFEB, the master transcriptional regulator of autophagy–lysosomal biogenesis, we can reverse the autophagy dysfunction of plaques, enhance aggrephagy of p62-enriched ...

Schematic illustration of the autophagy process in macrophages and recent advances in targeting autophagy for atherosclerotic treatments. Under conditions including nutrient insufficiency, hunger ...

This review discusses the cellular process of autophagy ... Liao, X, Sluimer, JC, Wang, Y, et al. Macrophage autophagy plays a protective role in advanced atherosclerosis. Cell Metab 2012;15:545-553.

X. Liao et al., “Macrophage autophagy plays a protective role in advanced atherosclerosis,” Cell Metabolism, 15:545-53, 2012. Atherosclerotic plaques can prompt heart attacks and strokes when ...

1. Understand the use of flow cytometry-based medium throughput screening assays as an essential tool to investigate macrophage phagocytosis. 2. Describe the role of pSTAT3 as a pro-phagocytic pathway ...

Role of PI3K/Akt/mTOR pathway-mediated macrophage autophagy in affecting the phenotype transformation of lung fibroblasts induced by silica dust exposure. August 28, 2023 ...

Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells. It allows your body to remove the dysfunctional cells.

TJS and JB are listed as inventors on a related patent, PCT/AU2020/050908 for measurement of autophagy in humans. “The anti-aging MIRACLE.” “Strengthen your immune system.” “Lose weight ...