Panelists discuss how the muscarinic pathway of xanomeline/trospium offers a safer, nondopaminergic approach to schizophrenia care. Panelists discuss how xanomeline/trospium chloride introduces a ...

Curcumin, a natural polyphenolic compound derived from Curcuma longa, has shown great potential in the prevention and treatment of chronic inflammatory diseases due to its significant antioxidant and ...

In this valuable study, the authors show the physiological response and molecular pathway mediating the effect of quinofumelin, a developed fungicide with an unknown mechanism. The authors present ...

Department of Chemical Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, 2-12-1-S1-13 Ookayama, Meguro-ku, Tokyo 152-8552, Japan ...

Divers found the Antikythera mechanism in a shipwreck in 1900. Zde via Wikimedia Commons under CC BY-SA 4.0 More than a century ago, a group of sponge divers discovered a shipwreck near the Greek ...

"I think [gepotidacin] gives a different side effect profile available to the clinicians, and I think for patients as well, it provides a better, more durable option over time," says Ryan Haumschild, ...

Hunger is an ancestral and evolutionary survival instinct; its importance is evident in the complex and redundant pathways involving all five senses that regulate it. 1,2 Historically, when humans ...

1 College of Art, Xiamen University, Xiamen, China 2 Department of Basic Medical Sciences, School of Medicine, Xiamen University, Xiamen, China Walking ability is essential for human survival and ...

The study provides a valuable showcase of a workflow to perform large-scale characterization of drug mechanisms of action using proteomics in which on-target and off-targets of 166 compounds using ...