A first-in-class antisense oligonucleotide — RES-010 (Resalis Therapeutics, Turin, Italy) — may complement and enhance the efficacy of antiobesity drugs such as GLP-1 receptor agonists (RAs), ...

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A microRNA (miRNA)-based liquid biopsy known as the Destinex assay demonstrated high accuracy sensitivity in identifying gastric cancer (GC), including early-stage cases, according to research ...

Abstract: It is well recognized that abnormal miRNA expression can result in drug resistance and pose a challenge to miRNA-based treatments. However, the drug-miRNA associations (DMA) are still ...

Sequence motifs and cleavage site specificity of DCL1 and other RNase III enzymes. (a) The GHR motifs define the DCL1 cleavage site. (b) Sequence motifs recognized by DCL1, Dicer, and Drosha, with ...

aeDepartment of Gastroenterology, Hepatology and Transplant Medicine, Medical Faculty, University of Duisburg-Essen, Essen, Germany afLaboratory of Metabolic Liver Diseases, Department of General, ...

The Guardant Reveal assay enables earlier detection of immunotherapy response in advanced solid tumors, surpassing conventional imaging methods. Changes in circulating tumor DNA (ctDNA) are strongly ...

Mirna Gonzalez opened Mirna’s Cuban Cuisine in 2016 in a tiny strip mall space on North Tamiami Trail near the airport. It quickly took off, thanks both to Gonzalez’s killer food and a dearth of ...