A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease ...

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

This syndrome arises from biallelic mutations in mismatch repair (MMR) genes, which are crucial for correcting DNA replication errors. As a result, individuals with CMMRD often experience multiple ...

Smoking and obesity synergistically worsened disease progression and cognitive performance in multiple sclerosis (MS) in a ...

Researchers are studying a new approach to HDFN prevention to reduce cases in countries where incidence rates remain high.

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During a presentation, Emmanuel S. Antonarakis, MD explained that homologous repair mutations and mismatch mutations in prostate cancer have therapeutic implications in the context of PARP inhibitors ...

Figure 2: Genetic map of 5p15.1 and genomic organization of ANKH. Figure 3: Cosegregation of ANKH mutations with the CMD phenotype. All eight families with mutations in ANKH are shown. We ...

Black fur comes from a genetic mutation that was likely in domesticated dogs thousands of years ago. The dark fur is rare in Europe due to a reduced genetic diversity, but at least half of the ...