Emerging drug-resistant strains are posing significant challenges to the global fight against tuberculosis (TB) and it is a critical task to detect treatment failure as early as possible.

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to ...

The Molecular Mechanics Poisson-Boltzmann Surface Area (MMPBSA) approach has been widely applied as an efficient and reliable free energy simulation method to model molecular recognition, such as for ...

Hence, it is important to have a rational in-silico design approach for molecular glues, which can significantly help with designing effective molecular glues using in-silico methods. In our previous ...

A multi-institutional study led by researchers at Children's Hospital of Philadelphia (CHOP) is the first to identify one of ...

Abstract: Breast cancer is one of the cancers of deep concern worldwide, and the molecular subtype of breast cancer is significant for patients' treatment selection, and prognosis judgment. The ...

A research team led by Dr. Huang Qing from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has ...

This method can measure the content of AGEs in full-thickness skin tissue and explore the molecular mechanism of skin glycation through temporal and spatial spectral changes. Raman signal spectroscopy ...

A multi-institutional study has identified one of the allergens responsible for eosinophilic esophagitis (EoE), an inflammatory disease of the esophagus. This is the first time one of the allergens ...

Quantum spin liquids (QSLs) are fascinating and mysterious states of matter that have intrigued scientists for decades. First ...

MDGen enhances molecular dynamics simulations through generative modeling, capturing time-series dynamics and reducing costs ...

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...