Recently, bioinformatics has emerged as a prominent subject within computer science, providing substantial insights into biology and human-related information. The primary challenge in bioinformatics ...

Abstract: The task of aligning DNA sequences has been pivotal in bioinformatics since the Needleman-Wunsch algorithm in 1970 [1]. Recent advances in sequencing technology have dramatically reduced the ...

MSA Transformer takes a multiple sequence alignment as an input to reveal conservation patterns, and is trained with Masked Language Modeling objectives to capture epistasis [1]. Previous research ...

TWILIGHT adopts the progressive alignment algorithm (Fig. 1c) and employs tiling strategies to band alignments (Fig. 1e). Combined with a divide-and-conquer technique (Fig. 1a), a novel heuristic ...