Objective: To study the clinical and pathological correlations of neuromuscular patients with a high aldolase and normal creatine kinase (CK) in serum at presentation or during a symptomatic ...

Letter Published: 24 August 2000 Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease) Ichizo Nishino, Jin Fu, Kurenai Tanji, Takeshi Yamada, Sadatomo ...

2.1 The composition of myofibrillar protein MP is divided into three categories according to their composition structure: (1) filament in, which is mainly composed of myosin and actin (2) regulatory ...

Mutations, A147T and A165V, within the ZM of ZASP-LΔex10 cause myofibrillar myopathy, but the mechanism is unknown. We have prepared these proteins, their ABR, and the respective mutant variants in ...

The diagnostic criteria of GNE myopathy include myopathy of early distal weakness, onset in early adulthood, mild or normal serum creatine kinase (CK) levels, rimmed vacuoles and detection of 14–18 nm ...

Editorial Archive Alcoholic Myopathy Published June 9, 1966 N Engl J Med 1966;274: 1326 - 1327 ...

Ullrich congenital muscular dystrophy and bethlem myopathy: clinical and genetic heterogeneity Distrofia muscular congênita com hiperextensibilidade articular distal (Ullrich) e miopatia de Bethlem: ...

Notably, myocardial LC3-II flux in the NTG control mice showed a progression increase from 1 to 6 m (Figure 1), suggesting that cardiac autophagic activities undergo a steady upregulation as the ...

This trial evaluated the efficacy of subcutaneous efgartigimod (PH20) administration in adults with active idiopathic inflammatory myopathy. The drug led to significant improvements in the Total ...

Capricor Therapeutics has completed its US marketing application for deramiocel, a cell therapy the US biotech hopes will become the first approved treatment for cardiomyopathy associated with ...

There have been multiple reports of toxicity when amiodarone is prescribed in combination with statins that are CYP3A4 substrates, particularly simvastatin. 92, 95 – 102 Pharmacokinetic data show an ...