When improperly folded proteins build up in the endoplasmic reticulum (ER), cells become stressed and conditions such as type ...

Researchers led by a team from the University of Bath in the UK have achieved just that in a basic worm model of Parkinson's.

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington’s, Alzheimer’s and Parkinson’s. But to the human eye, proteins that are ...

All mammals produce a version of the prion protein, but scientists don’t know what it normally does. In an altered form, the prion protein becomes an infectious agent that causes “mad cow disease” and ...

Scientists can also make normal proteins change into twisted proteins in the lab — but so far they haven't been able to show that those proteins can cause infections, Chesebro said. Chesebro said he's ...

In addition, the team discovered that plasma total tau—not just the modified pTau217 form—was elevated in newborns. This is ...

Researchers at Scripps have created T7-ORACLE, a powerful new tool that speeds up evolution, allowing scientists to design and improve proteins thousands of times faster than nature. Using engineered ...

SuperAgers defy normal aging by keeping sharp memories and healthy brains well into their 80s. Northwestern scientists discovered that these individuals either resist the buildup of harmful brain ...

Blood clots the size of raisins are normal during a heavy flow, but large, persistent clots may be a sign of an underlying ...