Researchers say findings help to bridge the structure of the genome to its function in managing how genes are turned on and off.

胰腺癌（Pancreatic Cancer）以胰腺导管腺癌（PDAC）最为常见，具有起病隐匿、早期转移、对化疗/免疫治疗敏感性差的特点，长期总体生存率低，仍是肿瘤学中预后最差的实体瘤之一。