A comprehensive, multi-phase investigation published in Advanced Science suggests that the amino acid tryptophan (Trp) may be a key determinant of therapeutic response to conventional synthetic ...

Department of Orthopedic Surgery, University of California, San Francisco, San Francisco, United States ...

Investigators have developed a prognostic model that may identify which patients with MIBC are suitable for bladder-preserving chemoradiation.

This study reveals that glycine decarboxylase (GLDC) promotes IgA nephropathy (IgAN) progression by enhancing mesangial cell ...

HIRI and liver transplantation animal models, primary cell co-cultures and adeno-associated virus-mediated gene knockdown were used to prove cellular ... site 2 (MEIS2), leading to increased ...

Alida Biosciences’ EpiPlex platform uses robust assay controls and specialized bioinformatics to detect RNA modification, genomic coordinates, and relative quantity.

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight ...

The 2024-25 Oklahoma City Thunder achieved dominant results by holding opponents to poor shooting from the field. It allowed a 51.3% effective field goal percentage (No. 1 in NBA) during the regular ...

Abstract: In this paper, differential gene expression (DGE) data in schizophrenia is analysed using machine learning approaches with the objective of predicting cell phenotypes related to the ...

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers. This study aimed to ...

Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...

Abstract: Accurately identifying differentially expressed genes from time-course RNA-Seq data is essential for understanding the dynamics of transcriptome changes during biological processes. Although ...