Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and lysosomes—coordinate the production of proteins, highlighting how interactions ...

A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor ...

Thought too hard to do, a new platform evolved proteins in mammalian cells, which could help researchers design drugs that work better in humans. “There are many, many examples, both published and ...

Scientists identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important 'co-stimulatory' factor that enhances the activation of ...

A study of 48 post-mortem brains found a protein that appears to protect brain cells from Alzheimer's — even in people who had significant amounts of amyloid plaques in their brains. Now a new insight ...

A protein notorious for its role in Alzheimer’s disease may hold the key to supercharging the aging immune system, according to new research. Scientists have found that a byproduct of amyloid-beta ...

Parkinson's disease is associated with toxic clumps of the alpha-synuclein protein in the brain, which disrupt healthy cell communication. Now, a new study shows another way this protein may damage ...

A team of scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) has created a protein-based therapeutic tool that could change the way we treat diseases caused by ...

Researchers in Bochum have discovered a control mechanism that may also operate beyond plants. Proteins carrying a "tail anchor" must be inserted into the ER membrane before they can fulfill their ...