Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each performing a specialized function. Researchers have long known that the ...

but this may change the protein’s structure or the way it moves in solution. Moreover a protein is often separately expressed and modified in order to perform 3D structure analysis, so ...

But not all target proteins were receptive to this method, called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not be ...

Renowned computational biologist Janet Thornton discusses the potential of protein structure understanding in developing new ...

Rice University researchers have revealed novel sequence-structure-property relationships for customizing engineered living ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to ...

“We were a good match because Martin and his group are interested in dynamics,” said Scaletti. “Not just the spatial structure of the protein but how it changes over time, and that seemed like a ...

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments ...

Unable to discern the change, the chaperones that guard ... Chaperones stabilize the cancerous proteins' unstable structure ...

Protein engineering largely relies on experiments that make incremental changes to proteins and study their effects ... The algorithm revealed that members of this superfamily share a pocket that ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...