Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each performing a specialized function. Researchers have long known that the ...
but this may change the protein’s structure or the way it moves in solution. Moreover a protein is often separately expressed and modified in order to perform 3D structure analysis, so ...
But not all target proteins were receptive to this method, called structure-based drug design. The 3-D structure of many proteins remained unavailable, and many important proteins could not be ...
The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...
Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to ...
“We were a good match because Martin and his group are interested in dynamics,” said Scaletti. “Not just the spatial structure of the protein but how it changes over time, and that seemed like a ...