Medtronic’s top ventilator executive began fielding pleas from world leaders' representatives five years ago, as pressure ...

一、慢阻肺病急性加重期的病理生理改变1. 慢阻肺病的核心病理改变（1）慢性气道炎症可以导致黏液栓的形成，气道内膜增宽；小气道慢性炎症持续进展，可以造成小气道严重狭窄、阻塞、塌陷等(图1)，进而导致呼气阻力增加。图1 COPD患者小气道病理改变图源：Lancet, 2004, ...